Karakura Town is the hometown of Ichigo Kurosaki. It is a small city with an average-sized population, most of which is unaware of the ghosts and spiritual forces that exist there.

Karakura Town is under the jurisdiction of 13th Division and is referred to as District 3600 by the Shinigami and is situated on the current jūreichi - the point in the Human World that possesses the greatest concentration of spiritual beings. For this reason Sōsuke Aizen sought to destroy it, as necessary to create a copy of the Ōken.